Animals that have been squeezed to death by snakes probably die of circulatory arrest rather than of suffocation as was thought.Scott Boback at Dickinson College in Carlisle, Pennsylvania, and his team anaesthetized rats and implanted probes and catheters to measure their heart rate, blood
Qubits — quantum bits which store and process information in quantum computers — can be controlled individually in a 3D structure without disturbing nearby atoms.Neutral atoms show promise as qubits when they are cooled and trapped by light, but manipulating one atom without disturbing
The history of attempts to spread scientific know-how beyond western centres of excellence is littered with failures. Capacity building needs long-term commitment, a critical mass of trainees, and a supportive home environment.
Earth's crust was thought to deform uniformly over most of the seismic cycle. Analysis of two centuries of nautical surveys from Chile reveals temporal variability that complicates our view of time-dependent seismic hazards.
Neuronal synapses in the brain adjust according to shifting demands as we experience the world. This synaptic plasticity forms the basis for critical periods in the visual and somatosensory – [Read More]
Functional Oxygen Sensitivity of Astrocytes Angelova, P. R., Kasymov, V., Christie, I., Sheikhbahaei, S., Turovsky, E., Marina, N., Korsak, A., Zwicker, J., Teschemacher, A. G., Ackland, G. L., Funk, G. D., Kasparov, S., Abramov, A. Y., Gourine, A. V.
Embryonic stem cell (ESC) cultures display a heterogeneous gene expression profile, ranging from a pristine naïve pluripotent state to a primed epiblast state. Addition of inhibitors of GSK3β and MEK (so-called 2i conditions) pushes ESC cultures toward a more homogeneous naïve pluripotent state, but the molecular underpinnings of this naïve transition are no […]
Welling, M., Chen, H.-H., Munoz, J., Musheev, M. U., Kester, L., Junker, J. P., Mischerikow, N., Arbab, M., Kuijk, E., Silberstein, L., Kharchenko, P. V., Geens, M., Niehrs, C., van de Velde, H., van Oudenaarden, A., Heck, A. J., Geijsen, N.
Epigenetic modifications, such as DNA methylation and histone modifications, are dynamically altered predominantly in paternal pronuclei soon after fertilization. To identify which histone modifications are required for early embryonic development, we utilized histone K-M mutants, which prevent endogenous histone methylation at the mutated site. We prepared […]
Ups1 forms a complex with Mdm35 and is critical for the transport of phosphatidic acid (PA) from the mitochondrial outer membrane to the inner membrane. We report the crystal structure of the Ups1-Mdm35-PA complex and the functional characterization of Ups1-Mdm35 in PA binding and transfer. Ups1 features a barrel-like structure consisting of an antiparallel […]
The composition of the mitochondrial membrane is important for its architecture and proper function. Mitochondria depend on a tightly regulated supply of phospholipid via intra-mitochondrial synthesis and by direct import from the endoplasmic reticulum. The Ups1/PRELI-like family together with its mitochondrial chaperones (TRIAP1/Mdm35) represent a unique he […]
Miliara, X., Garnett, J. A., Tatsuta, T., Abid Ali, F., Baldie, H., Perez-Dorado, I., Simpson, P., Yague, E., Langer, T., Matthews, S.
A study finds that pain hypersensitivity in male and female mice is differentially dependent on microglia and T cells, and describes a sex-specific response to microglia-targeted pain treatments. This sex difference will be important to consider when developing treatments for pain and other neurological disorders involving microglia and immune cells.
How do neurons combine distinct information streams and form long-lasting associations? Dendritic plateau potentials may allow the integration and storage of coincident location and contextual information in hippocampal neurons.
The confidence that we place in our decisions can affect the judgments themselves. The BOLD signal in ventromedial prefrontal cortex automatically reflects the relationship between confidence and judgments on a range of tasks.
Arkive’s Week in Review — Wildlife News ICYMI: Arkive has compiled some of the biggest and most interesting headlines from this week. Article originally published on Friday, Jun 26, 2015 More endangered pygmy sloths discovered in Panama than previously estimated Researchers estimate that there are between 500 – 1500 pygmy sloths residing on the Isla […] […]
Arkive’s Week in Review — Wildlife News ICYMI: Arkive has compiled some of the biggest and most interesting headlines from this week. Article originally published on Friday, Jun 19, 2015 Hawk-moths are capable of slowing their brains to stay in rhythm with their environment Hawk moths can slow parts of their brain in order to […]
Arkive’s Week in Review — Wildlife News ICYMI: Arkive has compiled some of the biggest and most interesting headlines from this week. Article originally published on Friday, Jun 12, 2015 U.S. grants new protections for captive chimpanzees On June 12th the US Fish and Wildlife Service declared that all chimpanzees both in the wild and […]
Do you love camels as much we do? The Arkive Team had the wonderful opportunity to chat with the amazing folks at the Wild Camel Protection Foundation to learn all about what they do and their current essay competition with cash prizes! Can camels drink saltwater? Did you know that you can help camel conservation right […]