The sugary drops that form on the edges of wounds in a particular plant species have been identified as nectar, which attracts the enemies of leaf-eating pests.Plants usually heal wounds quickly, but injuries to the bittersweet nightshade (Solanum dulcamara) do not close
A worldwide switch to vegetarian diets could allow the planet's estimated 2050 population of 9.7 billion to feed themselves without cutting down any more forests.Karl-Heinz Erb and his colleagues at the University of Klagenfurt in Vienna created a model of the global agricultural system
Investigations of sexual harassment are difficult and potentially destructive to all involved. It is imperative that they are carried out quickly, with high priority and acted upon decisively where misconduct is identified.
The Paris Agreement introduced three mitigation targets. In the future, the main focus should not be on temperature targets such as 2 or 1.5 °C, but on the target with the greatest potential to effectively guide policy: net zero emissions.
Phosphorus is essential for food production, but it is also a key cause of eutrophication. Estimates of phosphorus flux for the past 40–70 years reveal that large river basins can experience phases of phosphorus accumulation and depletion.
Mis18 is a key regulator responsible for the centromere localization of the CENP-A chaperone Scm3 in Schizosaccharomyces pombe and HJURP in humans, which establishes CENP-A chromatin that defines centromeres. The molecular and structural determinants of Mis18 centromere targeting remain elusive. Here, by combining structural, biochemical, and yeast genetic s […]
Subramanian, L., Medina-Pritchard, B., Barton, R., Spiller, F., Kulasegaran-Shylini, R., Radaviciute, G., Allshire, R. C., Arockia Jeyaprakash, A.
Ku heterodimer is a DNA binding protein with a prominent role in DNA repair. Here, we investigate whether and how Ku impacts the DNA damage response by acting as a post-transcriptional regulator of gene expression. We show that Ku represses p53 protein synthesis and p53-mediated apoptosis by binding to a bulged stem-loop structure within the p53 5' UTR. […]
Lamaa, A., Le Bras, M., Skuli, N., Britton, S., Frit, P., Calsou, P., Prats, H., Cammas, A., Millevoi, S.
Yap1 is a transcriptional co-activator of the Hippo pathway. The importance of Yap1 in early cell fate decision during embryogenesis has been well established, though its role in embryonic stem (ES) cells remains elusive. Here, we report that Yap1 plays crucial roles in normal differentiation rather than self-renewal of ES cells. Yap1-depleted ES cells maint […]
Chung, H., Lee, B.-K., Uprety, N., Shen, W., Lee, J., Kim, J.
Connectivity patterns of neocortex exhibit several odd properties: for example, most neighboring excitatory neurons do not connect, which seems curiously wasteful. Brunel's elegant theoretical treatment reveals how optimal information storage can naturally impose these peculiar properties.
Hypothalamic Agouti-related peptide (AgRP)-expressing neurons promote feeding via inhibitory mechanisms. A downstream target in the medial amygdala both mediates feeding and modulates risk-taking and defensive behaviors in the face of starvation.
The neurobiology of social behavior is highly complex and defects are present in several mental illnesses. Here Barak and Feng discuss neurobiological aspects of two neuropsychiatric disorders presenting opposite social behavior abnormalities, autism spectrum disorder and Williams syndrome.
The prefrontal cortex supports the expression and inhibition of fear- and reward-related behaviors. These dualities are attributable to discrete functional domains making up this brain region, which allow it to stimulate or inhibit behavior depending on an organism's experiences. The authors review evidence that supports, or refutes, this “go/stop” func […]
Well done to everyone who took part in our #GuessThePenguin quiz for World Penguin Day. You all have great identification skills when it comes to these very handsome creatures! We can now reveal the answers to the mystery penguins we posted on social media, but we didn’t want to ruin it for those who didn’t […]
Cephalopods are arguably the weirdest of all marine invertebrates. The name cephalopod literally translates to ‘head-footed’ in Greek, indicating just how strange members of this taxonomic class are, but nothing in their name indicates how incredibly intelligent they are. Their alien-like features are truly fascinating and cephalopods are commonly regarded a […]
Arkive and Wildscreen Exchange photographer James Warwick recently visited the Kanha National Park in Madhya Pradesh, which is located in the Central Indian Highlands. This name may not mean much to you but it is, in fact, the setting for Rudyard Kipling’s ‘Jungle Book’ and is home to the tigers, sloth bears and Indian leopards […]
Did you know that April 17th is observed annually as Bat Appreciation Day? Love them or hate them, there are over 1,200 bat species around the world and they play a huge role in the health of our ecosystems. Although scary to some and shrouded in many superstitions, the worlds’ only flying mammals are extremely […]