Gut microbes are important for digestion and immunity in humans — and may also be beneficial to bees.Waldan Kwong at Yale University in New Haven, Connecticut, and his colleagues hand-reared larvae of the honeybee (Apis mellifera; pictured) in the laboratory. They allowed
Helium is a famously inert element, but researchers have made a stable compound from helium and sodium.Artem Oganov at Stony Brook University in New York and his colleagues used an algorithm to look for potentially stable helium compounds and predicted that Na2He
Groundwater resources are directly affected by climate variability via precipitation, evapotranspiration and recharge. Analyses of US and India trends reveal that climate-induced pumping indirectly influences groundwater depletion as well.
The twin isotopic signatures of the Moon and Earth are difficult to explain by a single giant impact. Impact simulations suggest that making the Moon by a combination of multiple, smaller moonlet-forming impacts may work better.
The dynamics of polar marine ecosystems are poorly understood. A laser-based space-borne sensor captures annual cycles of phytoplankton biomass in seasonally ice-free polar waters, and provides clues on how growth drives these cycles.
Atmospheric oxygen was maintained at low levels throughout huge swathes of Earth's early history. Estimates of phosphorus availability through time suggest that scavenging from anoxic, iron-rich oceans stabilized this low-oxygen world.
The functional role of the ubiquitin-proteasome pathway during maternal-to-zygotic transition (MZT) remains to be elucidated. Here we show that the E3 ubiquitin ligase, Rnf114, is highly expressed in mouse oocytes and that knockdown of Rnf114 inhibits development beyond the two-cell stage. To study the underlying mechanism, we identify its candidate substrat […]
Yang, Y., Zhou, C., Wang, Y., Liu, W., Liu, C., Wang, L., Liu, Y., Shang, Y., Li, M., Zhou, S., Wang, Y., Zeng, W., Zhou, J., Huo, R., Li, W.
In the mitotic spindle, kinetochore microtubules form k-fibers, whereas overlap or interpolar microtubules form antiparallel arrays containing the cross-linker protein regulator of cytokinesis 1 (PRC1). We have recently shown that an overlap bundle, termed bridging fiber, links outermost sister k-fibers. However, the relationship between overlap bundles and […]
Mitochondrial trafficking is influenced by neuronal activity, but it remains unclear how mitochondrial positioning influences neuronal transmission and plasticity. Here, we use live cell imaging with the genetically encoded presynaptically targeted Ca2+ indicator, SyGCaMP5, to address whether presynaptic Ca2+ responses are altered by mitochondria in synaptic […]
Vaccaro, V., Devine, M. J., Higgs, N. F., Kittler, J. T.
MicroRNA (miRNA)-guided mRNA repression, mediated by the miRNA-induced silencing complex (miRISC), is an important component of post-transcriptional gene silencing. However, how miRISC identifies the target mRNA in vivo is not well understood. Here, we show that the nucleoporin Nup358 plays an important role in this process. Nup358 localizes to the nuclear p […]
Sahoo, M. R., Gaikwad, S., Khuperkar, D., Ashok, M., Helen, M., Yadav, S. K., Singh, A., Magre, I., Deshmukh, P., Dhanvijay, S., Sahoo, P. K., Ramtirtha, Y., Madhusudhan, M. S., Gayathri, P., Seshadri, V., Joseph, J.
We present a special set of Review articles on neuroimmune communication that highlight how the immune system and nervous system are anatomically connected, mechanistically communicate and reciprocally influence the other's function.
Representations in excitatory neurons generally narrow as they are refined. Odor representations in interneurons, however, broaden with maturation and learning, as connections between interneurons and projection neurons expand.
The biological drive to consume salt ensures that we consume adequate sodium for survival. In this issue of Nature Neuroscience, two articles provide insight into the neurons and circuits that regulate sodium appetite.
Many spatial correlates have been identified that form the neural basis for navigation. Two studies have now uncovered a new cell type: bidirectional cells, which fire when the head is pointing in one of two opposing directions.
Today the dingo has been crowned the World’s Favourite Unloved Species, after two weeks of voting and some fierce competition. Here Bret Charman discusses his experiences with photographing this misunderstood yet beautiful species. The world’s wild dog species, for the most part, are on a downward spiral – none more so than the iconic dingo […]
#LoveSpecies nominee: helmeted hornbill Nominated by: World Land Trust Why do you love it? The fierce appearance of the world’s largest hornbill, with a battering ram of solid keratin fixed to their face, suits its medieval mating rituals. The males clash mid-air in head-to-head combat (an impressive display called aerial jousting) to win access to fruiting […]
#LoveSpecies nominee: Galapagos giant tortoise Nominated by: Ecology Project International Why do you love it? The Galapagos giant tortoise has had such an impressive impact on history, science, and its ecosystem that it’s sure to win over hearts. Endemic to the Galapagos Islands off the coast of Ecuador, this tortoise is one of only two distinct […]
#LoveSpecies nominee: okapi Nominated by: Tusk Task Force Why do you love it? Even though the okapi resembles the striped markings of a zebra on its behind, it is actually closely related to their tall cousins, the giraffe. Due to their common remarkable DNA, the okapi and the giraffe are the only living members of the family, […]